Co-Diovan 320/12.5 mg

Manufacturer: Novartis

Pharmaceutical name: Valsartan, Hydrochlorothiazide

Pack: 1 pack (28 tabs (320 mg/12.5 mg))

Co-Diovan film-coated tablets contain two active ingredients, Valsartan and Hydrochlorothiazide, which work together to manage high blood pressure (hypertension). This medication combines the effects of both Valsartan, an ARB blocker targeting angiotensin II, and Hydrochlorothiazide, which acts on the distal convoluted tubules to inhibit sodium chloride transport. This inhibition leads to increased urine production, thereby lowering blood pressure.

Valsartan falls under the category of medications known as “angiotensin II receptor antagonists,” which help regulate high blood pressure. Angiotensin II is a compound in the body responsible for constricting blood vessels, resulting in elevated blood pressure. Valsartan counteracts the effects of angiotensin II, allowing blood vessels to relax and subsequently reducing blood pressure.

Hydrochlorothiazide is part of the group referred to as thiazide diuretics, sometimes known as “water tablets.” It enhances urine production, which contributes to lowering blood pressure as well.

Co-Diovan is indicated for the treatment of high blood pressure that cannot be effectively managed with a single medication alone.

High blood pressure places additional strain on the heart and arteries. If left untreated, it can damage the blood vessels in the brain, heart, and kidneys, potentially leading to a stroke, heart failure, or kidney failure. Furthermore, high blood pressure raises the likelihood of heart attacks. Bringing your blood pressure to a normal level mitigates the risk of developing these conditions.

Side effects may include headache, dizziness, a spinning sensation, blurred vision, drowsiness, fatigue or weakness, back or joint pain, runny or bleeding nose or sinus congestion, dry cough, sore throat or hoarseness, dry mouth, diarrhea, constipation or flatulence, nausea, vomiting, decreased appetite, stomach discomfort or indigestion, back pain, muscle pain, muscle tenderness or weakness, cramps or joint pain, tingling or numbness in the extremities, blistering of the skin, accelerated sunburn symptoms, and difficulty sleeping.